一 、Background Introduction

Animal facilities for laboratory testing are specific living environments for experimental animals. Environmental conditions not only affect the quality of experimental animals, but also directly affect the scientificity, sensitivity of animal reactions, and repeatability of experiments. Therefore, it is necessary to strictly control the environmental conditions of experimental animal facilities and meet the requirements of environmental control indicators, including isolators, independent ventilation systems (IVC), and other experimental animal feeding devices that must also meet environmental standards.

二 、Basis for Testing

GB14925-2010 "Laboratory Animal Environment and Facilities"

三 、Example of Specific Implementation

Before the start of our animal facility, we not only conduct routine tests on environmental temperature, humidity, and other indicators, but also continuously monitor environmental microorganisms. The detection points include exhaust ports and sentinel mouse bedding, and we conduct long-term monitoring of dynamic environmental microorganisms, from the number of microorganisms to bacterial identification. Adding environmental monitoring on the basis of animal monitoring can better predict the occurrence of microbial infections in experimental animals.

四、Testing Conditions

Static monitoring of barrier environment

Dynamic monitoring of barrier environment

Static monitoring of isolation environment

Dynamic monitoring of isolation environment

五 、V. Detection items